NARCOLEPSY, SYMPTOMS AND SCIENCE

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Introduction

Nausea and sleepiness are common symptoms of narcolepsy. As a result, patients with narcolepsy find it difficult to stay awake. Regardless of the circumstances, it is tough to remain awake for long periods of time. It’s possible that narcolepsy will have a negative impact on your daily life.
Narcolepsy is most often caused by a loss of muscle tone (cataplexy) brought on by strong emotions. Cataplexy-inducing narcolepsy is a subtype of narcolepsy type 1. This kind of narcolepsy, known as Kind 2, does not cause cataplexy.
Both sleep apnea and narcolepsy fall under the umbrella of the term narcolepsy.
The most common kind is Type 1. To put it simply, hypocretin and orexin are two distinct names for hypocretin.
It is not a symptom of Narcolepsy type 2 to have cataplexy (sleep apnea). In most cases, hypocretin levels in people with type 2 narcolepsy are normal.

Symptoms and signs of narcolepsy may worsen in the first several years. They, on the other hand, will last a lifetime. Here are a few examples:

My mouth has been watering all day. With narcolepsy, sleepiness occurs when and where it is least expected. For up to a half-hour, you may be doing work or talking to pals when you fall asleep.
Wakefulness is a pleasant sensation, but it swiftly fades into sleep. It’s possible that medicines like Modvigil and Modalert 200 may assist with this.
You may notice a decrease in your ability to focus and concentrate throughout the day. First and foremost, the constant drooling that disrupts one’s ability to concentrate and work is a sign of a serious condition.

Constantly disrupted sleep
Patients with this illness may have difficulty falling asleep at night, followed by uncontrollable drowsiness throughout the daytime. There is no excess sleep in narcolepsy sufferers, but there is a great deal of fluctuation in their sleep schedules both throughout the day and night.
Excessive daytime drowsiness.
The most common symptom of narcolepsy is excessive daytime sleepiness, which is also known as EDS. In those with EDS, poor concentration and weariness are symptoms of chronic fatigue syndrome. “microsleep,” which occurs when individuals fall asleep for only a few seconds without even realising it and go on with their daily activities, such as writing or driving, may disturb this pattern of sleep.

A long-term sleep disorder, narcolepsy, may affect anybody. Treatments may help you cope with your symptoms even if there is no cure.
Patients with this condition may benefit from medication, lifestyle adjustments, and abstaining from dangerous behaviours.
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There are several options for treating the condition, including:

Nuvigil, modafinil (Provigil), and methylphenidate are examples of stimulant medications (Ritalin). This medicine might cause nausea, headaches, and anxiety as adverse effects. They can all keep you awake at the same time.
Some of the side effects include constipation, insomnia, sleeplessness, and weight gain. Venlafaxine is used to treat hallucinations, cataplexy, and sleep paralysis (Effexor).
SSRIs block the absorption of serotonin (SSRIs). Taking an SSRI like fluoxetine may help you have a better night’s sleep and feel calmer (Prozac). There is, however, the possibility of dizziness and a dry mouth.
Tricyclic antidepressants include nortriptyline and amitriptyline. Dry mouth, constipation, and urine retention are all possible side effects of these older medications.
The FDA has authorised sodium oxybate Xyrem as the only treatment for cataplexy and excessive drowsiness in the morning. Having a discussion with your doctor about the benefits and drawbacks of this medication might be useful. There might be a host of other unpleasant outcomes in addition to sadness, nausea, and thirst.
The release of histamines in the brain by pitolisant Wakix helps to reduce daytime sleepiness. It has been authorised by the FDA as a treatment for narcolepsy. Among the possible side effects include nausea, headaches, anxiety, and insomnia.