The Latest Cannabinoid
The hemp plant (Cannabis sativa) contains a wide range of chemical compounds. Cannabinoids, which are well-known for their various therapeutic properties, are among these compounds.
THC (tetrahydrocannabinol) and CBD are the two most active cannabinoids found in hemp (cannabidiol). While THC is an intoxicating compound that causes marijuana users to become “high,” CBD has no intoxicating properties and can be used to treat a wide range of medical conditions.
CBD-infused wellness products have grown in popularity in recent years, owing to their anti-inflammatory, analgesic, and anti-oxidant properties. Because CBD is one of the most abundant compounds in the hemp plant, it is simple to isolate and extract, and can thus be efficiently scaled to produce a wide range of commercial products.
Bulk CBG Isolate, or cannabigerol, is a non-intoxicating cannabinoid discovered in the hemp plant that has similar therapeutic potential. CBG, while less abundant than CBD, has the potential to treat a variety of health issues such as inflammation, pain, and anxiety.
Continue reading to learn more about Bulk CBG Isolate and its applications. The following questions will be addressed in the remainder of this article:
- What exactly is CBG?
- How is it obtained?
- What therapeutic benefits could it have?
- What is the distinction between CBG and CBD?
- Why is CBG more costly than CBD?
- How do I pick the best CBG product?
- How is CBG examined?
What Exactly is CBG?
CBG, or cannabigerol, is a cannabinoid found in trace amounts in hemp plants. It is the precursor molecule for other cannabinoids, which means that when CBG-A (the acidic and inactive form) is heated, it degrades to form CBD, CBG, CBC, and THC.
Because CBG accounts for about 1% of the hemp plant, it is difficult to obtain sufficient quantities for thorough research. Indeed, while researchers believe CBG is thousands of years old, we still know very little about its composition and medicinal uses.
Nonetheless, in-vitro studies with rats have shown that Bulk CBG Isolate may improve symptoms of medical conditions such as colitis, glaucoma, and neurodegeneration.
CBG Discovery: Extraction Methods and Difficulties
Chromatography is used to extract CBG from the hemp plant. This procedure consists of three major steps:
- Hemp is dissolved in a superfluid liquid solvent (such as CO2 or ethanol), which extracts the plant’s cannabinoids.
- The solution is then evaporated under vacuum to remove all gases, yielding a highly pure CBG concentrate.
- To maintain potency, the concentrate (along with finished CBG products) is stored at room temperature away from direct sunlight.
Given the apparent simplicity of this extraction process, as well as the fact that Bulk CBG Isolate has numerous medicinal applications and no intoxicating effects, one might wonder why CBG hasn’t gained the same popularity as CBD.
There are several possible answers to this question, but the main reason is most likely the high cost of extraction.
CBG, dubbed the “Rolls-Royce of cannabinoids,” is the most expensive cannabinoid to isolate. Why? Because hemp contains only trace amounts of CBG, it takes thousands of pounds of biomass to produce a small amount of CBG.
Furthermore, CBG extraction employs specialised manufacturing equipment. Because the levels extracted are relatively low, the high-performance chromatography apparatus used to isolate and purify the cannabinoid extract must be extremely precise in order to make the most of the limited raw plant material.
CBG, in addition to its costs, causes difficulties for farmers. This is because the longer a hemp plant matures, the more likely CBG-A and CBG will break down into CBD and other cannabinoids. Cultivators can either grow cannabis solely for the production of CBG, or they can allow the crop to fully mature and sell it with a lower CBG content for other purposes.
Advantages of CBG
As previously stated, research on CBG is limited. However, some research suggests that the cannabinoid has a number of medicinal benefits. Let’s look at some of the health conditions that CBG may be able to treat:
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Colitis and Inflammatory Bowel Disease (IBD)
IBS and colitis are diseases that cause inflammation and ulcers in the lining of the large intestine (colon) and rectum.
According to a 2013 mouse study, Bulk CBG Isolate may help to alleviate the painful symptoms of colitis. Another study found that using Wholesale CBG Isolate improved the following symptoms in IBD patients: abdominal pain, cramping, poor appetite, diarrhea, weight loss, and nausea. However, the isolated effect of CBG on these symptoms requires further investigation.
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Intraocular Pressure and Glaucoma
Glaucoma is an eye condition that can damage the optic nerve and is frequently caused by abnormally high eye pressure (intraocular pressure).
CBG and other related cannabinoids, according to two studies conducted in 1990 and 2008, may be partially responsible for reducing the severity of glaucoma and intraocular pressure. This could have huge implications because, while patients are currently using THC to manage their glaucoma, CBG offers a non-intoxicating solution.
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Dysfunction of the Bladder
In 2015, researchers concluded that Wholesale CBG Isolate showed promise in improving bladder dysfunction and contractions in mice after comparing five cannabinoids.
Infections caused by bacteria
MRSA (Methicillin-Resistant Staphylococcus Aureus) is a potentially fatal bacterial infection that is resistant to the antibiotic methicillin. A 2008 study found that CBG could be a promising antibacterial agent capable of rendering drug-resistant bacteria ineffective.
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Other Neurodegenerative Diseases and Huntington’s Disease
Huntington’s disease is a progressive brain disorder. It is caused by a faulty gene that causes changes in the central region of the brain, affecting movement, mood, and cognitive abilities.
In 2015, a mouse study found that Wholesale CBG Isolate, alone or in combination with other phytocannabinoids and medicinal therapies, could help with neurodegenerative diseases like Huntington’s disease. CBG was discovered to normalise the expression of abnormal genes linked to brain degeneration, highlighting its potential as a neuroprotective compound.
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Pain Relief and Appetite Loss
A 2016 rat study found that Wholesale CBG Isolate may help to stimulate and improve appetite, and may be useful for those suffering from conditions such as HIV or post-chemotherapy complications.
Furthermore, a 2017 study discovered that CBG may act as an anti-oxidant and be effective in the treatment of pain and inflammation.
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GABA Receptor Inhibition Re-uptake
GABA (Gamma-aminobutyric acid) is an amino acid that occurs naturally and acts as a neurotransmitter (or chemical messenger) in the brain. GABA uptake inhibitors reduce the amount of GABA absorbed and are commonly used to treat anxiety.
A 1975 study concluded that CBG inhibits GABA uptake. Promotes muscle relaxation and tension relief, and induces feelings of peace and calm in the brain.
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Inflammation and Disease of the Skin
A 2007 study looked into CBG’s ability to treat skin conditions like psoriasis and eczema. The cannabinoid has the potential to reduce inflammation, pain, and swelling in these conditions, according to the researchers.
While all of the studies mentioned above demonstrate CBG’s therapeutic potential in the pharmacological realm. It is important to note that they do not prove that Bulk CBG Isolate causes certain health benefits directly and invariably. More research is needed to fully comprehend how Wholesale CBG Isolate works in the human body.
CBG versus CBD
Because Wholesale CBG Isolate is the precursor compound for CBD, the properties and composition of the two cannabinoids differ. There are, however, some parallels between the two.
For starters, both have the potential to alleviate a variety of medical conditions. Second, CBG and CBD are both non-intoxicating, which means they do not impair one’s mental state or cognitive functioning. Simply put, neither compound will get you “high,” but they may help to alleviate anxiety, pain, and depression symptoms.
CBG is particularly important because, like CBD, it can help to counteract the mind-altering effects of THC. According to research, CBG activates the nervous system’s CB1 receptor in a similar way to CBD, reducing psychoactivity. This means that consuming cannabis with a high concentration of both CBD. Wholesale CBG Isolate, or consuming a CBG isolate while smoking or eating cannabis, may be able to significantly offset any intoxication.
When it comes to the differences between CBD and CBG. One of the most notable differences is that CBD has a relatively low affinity. For cannabinoid receptors found in our bodies, and it mostly interacts with our natural endocannabinoid system indirectly. CBG, on the other hand, is thought to interact directly with the CB1 and CB2 cannabinoid receptors in our brain.
Why is CBG more costly than CBD?
CBG is more difficult to extract than CBD. Other cannabinoids because it only accounts for 1% of the total cannabis plant. It also implies that CBG crops must be harvested earlier in order to produce high yields. As a result, CBG is the most costly cannabinoid to produce.
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